Work in this area focuses on the basic processes by which cancers arise, progress, and respond to or resist therapy. Researchers seek to understand how cancer cells transform, metastasize, and interact with their microenvironment; to study the genetic and cell signaling mechanisms that drive disease; and to develop innovative, targeted strategies to control cancer processes.
Heads of Laboratories
- C. David Allis, Ph.D.
Laboratory of Chromatin Biology and Epigenetics
- Kivanç Birsoy, Ph.D.
Laboratory of Metabolic Regulation and Genetics
- Paul Cohen, M.D., Ph.D.
Laboratory of Molecular Metabolism
- Robert B. Darnell, M.D., Ph.D.
Laboratory of Molecular Neuro-oncology
- Titia de Lange, Ph.D.
Laboratory of Cell Biology and Genetics
- Elaine Fuchs, Ph.D.
Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development
- Hironori Funabiki, Ph.D.
Laboratory of Chromosome and Cell Biology
- Tarun Kapoor, Ph.D.
Selma and Lawrence Ruben Laboratory of Chemistry and Cell Biology
- Richard P. Lifton, M.D., Ph.D.
Laboratory of Human Genetics and Genomics
- Michel C. Nussenzweig, M.D., Ph.D.
Laboratory of Molecular Immunology
- Michael O'Donnell, Ph.D.
Laboratory of DNA Replication
- Robert G. Roeder, Ph.D.
Laboratory of Biochemistry and Molecular Biology
- Sanford M. Simon, Ph.D.
Laboratory of Cellular Biophysics
- Agata Smogorzewska, M.D., Ph.D.
Laboratory of Genome Maintenance
- Hermann Steller, Ph.D.
Strang Laboratory of Apoptosis and Cancer Biology
- Sohail Tavazoie, M.D., Ph.D.
Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology